Caffeine, friend or foe for headaches and migraine?

Caffeine is a common part of many people’s daily routine, whether in coffee, tea, or certain medications. It’s well-known for its ability to increase alertness and improve concentration, but its impact on headaches and migraines is more complex. For some, caffeine can provide significant relief from headache symptoms, while for others, it can be a hidden trigger for pain. Understanding how caffeine interacts with your body and its role in headache management is crucial for those who suffer from frequent headaches or migraines.

In certain cases, caffeine can be an effective treatment for headaches, particularly tension headaches and migraine. Caffeine helps by narrowing blood vessels, which can alleviate headache pain. It is often included as an active ingredient in many over-the-counter headache medications (such as Excedrin) because it can enhance the effects of pain relievers like aspirin, ibuprofen (advil), and acetaminophen (Tylenol).

Caffeine can trigger migraine attacks in some individuals due to its impact on the brain’s blood vessels and neurotransmitters. While small amounts of caffeine can provide temporary relief by constricting blood vessels, habitual consumption may lead to dependence. When caffeine levels drop or are withdrawn, the sudden expansion of blood vessels can provoke a migraine, as the brain becomes more sensitive to fluctuations in caffeine intake. Additionally, caffeine can affect serotonin levels, which are closely linked to migraine onset, making some people more prone to experiencing migraines after consuming even small amounts.

Several studies and randomized clinical trials (RCTs) have been conducted to evaluated caffeine’s effect on migraine. The evidence is mixed, as caffeine has been shown to both relieve and trigger migraine attacks. It's important to evaluate how caffeine affects your own headaches and whether it helps or worsens your symptoms. Discuss your caffeine consumption with your provider, as excessive intake can lead to negative effects and complicate headache management.

 

References:

Cohen F, Bobker S. From diet to disasters, lifestyle factors can affect headaches and migraine. Headache. 2023 Jun;63(6):712-713. doi: 10.1111/head.14500.

Nowaczewska M, Wiciński M, Kaźmierczak W. The Ambiguous Role of Caffeine in Migraine Headache: From Trigger to Treatment. Nutrients. 2020 Jul 28;12(8):2259. doi: 10.3390/nu12082259.

Alstadhaug KB, Andreou AP. Caffeine and Primary (Migraine) Headaches-Friend or Foe? Front Neurol. 2019 Dec 3;10:1275. doi: 10.3389/fneur.2019.01275. 

Zhang L, Yin J, Li J, Sun H, Liu Y, Yang J. Association between dietary caffeine intake and severe headache or migraine in US adults. Sci Rep. 2023 Jun 23;13(1):10220. doi: 10.1038/s41598-023-36325-8. Erratum in: Sci Rep. 2023 Sep 29;13(1):16391. doi: 10.1038/s41598-023-43648-z

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